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病原生物学研究所

个人简介

金奇,1959年生,籍贯四川,病原微生物学家,病原生物学研究所研究员,博士生导师。1978年考入北京医学院基础医学专业,1983年获得学士学位。1985年在中国预防医学科学院微生物与免疫专业攻读博士学位,从事痘苗病毒基因组研究,1990年获得博士学位。1990年进入美国联邦疾病预防与控制中心国家传染病中心进行博士后研究工作,主要从事天花病毒基因组及肠道病毒分子流行病研究。 1995年回国后晋升为副研究员,1996年破格晋升为研究员。


主要研究方向

主要从事重要病原微生物基因组、蛋白质组、抗体组等组学研究,同时开展重要病原体(病毒/细菌)的病原学和分子流行病学等研究


代表性成果

皇冠足球90比分

图片

1. Zhiqiang Wu #*,  Yelin Han#,  Bo Liu#,  Hongying Li,  Guangjian Zhu, Alice Latinne, Jie Dong,  Lilin Sun, Haoxiang Su,  Liguo Liu, J iang Du,  Siyu Zhou,  Mingxing Chen,  Anamika Kritiyakan, Sathaporn Jittapalapong, Kittipong Chaisiri, Phillipe Buchy, Veasna Duong, Jian Yang, Jinyong Jiang, Xiang Xu, Hongning Zhou, Fan Yang, David M. Irwin, Serge Morand, Peter Daszak, Jianwei Wang, Qi Jin*. Decoding the RNA viromes in rodent lungs provides new insight into the origin and evolutionary patterns of rodent-borne pathogens in Mainland Southeast Asia.  Microbiome, 2021, 9(1):18. (IF=16.837)

2. Feng Jiang#,  Ningning Li#, Xia Wang#, Jiaxuan Cheng#, Yaoguang Huang, Yun Yang, Jianguo Yang, Bin Cai, Yi-Ping Wang, Qi Jin*, Ning Gao*. Cryo-EM structure and assembly of an extracellular contractile injection system. Cell, 2019, 177(2):370-383. (IF=38.637)

3. Lei Gao#*, Haoran Zhang#, Henan Xin#, Jianmin Liu#, Shouguo Pan#, Xiangwei Li, Ling Guan, Fei Shen, Zisen Liu, Dakuan Wang, Xueling Guan, Jiaoxia Yan, Hengjing Li, Boxuan Feng, Xuefang Cao, Yu Chen, Wei Cui, Zongde Zhang, Yu Ma, Xiaoyou Chen, Xinhua Zhou, Qi Jin*. for the LATENTTB - NSTM study team. Short-course regimens of Rifapentine plus Isoniazid to treat Latent Tuberculosis Infection in older Chinese: a randomized controlled study. Eur Respir J. 2018, 52 (6): 1801470. (IF=11.807)

4. Lei Gao#, Xiangwei Li#, Jianmin Liu#, Xinhua Wang#, Wei Lu#, Liqiong Bai#, Henan Xin, Haoran Zhang, Hengjing Li, Zongde Zhang, Yu Ma, Mufei Li, Boxuan Feng, Jiang Du, Hongtao Sui, Rong Zhao, Haoxiang Su, Shouguo Pan, Ling Guan, Fei Shen, Jian He, Shumin Yang, Hongyan Si, Xu Cheng, Zuhui Xu, Yunhong Tan, Tianzhu Chen, Weiguo Xu, Hong Peng, Zhijian Wang, Tao Zhu, Xiaoyou Chen, Xinhua Zhou, Xueling Guan, Qi Jin*, for the LATENTTB-NSTM study team. Incidence of active tuberculosis among individuals with latent tuberculosis infection in rural China: follow-up results of a population-based multicenter prospective cohort study. Lancet Infect Dis. 2017,17(10):1053-1061. (IF=25.148 C100)

5. Zhe Chen#, Jianmin Wang#, Linlin Bao#, Li Guo#, Weijia Zhang, Ying Xue, Hongli Zhou, Yan Xiao, Jianwei Wang#, Fan Wu#, Ying Deng*, Chuan Qin*, Qi Jin*. Human monoclonal antibodies targeting the Hemagglutinin glycoprotein canneutralize H7N9 influenza virus. Nat Commun. 2015, 6:6714. (IF=11.329)

6. Lei Gao#, Wei Lu#, Liqiong Bai#, Jinhua Wang#, Jinsheng Xu#, Antonino Catanzaro, Vicky Cárdenas, Xiangwei Li, Yu Yang, Jiang Du, Hongtao Sui, Rong Zhao,Yinyin Xia, Mufei Li, Boxuan Feng, Zhen Li, Henan Xin, Huiting Wang, Jianmin Liu, Shouguo Pan, Fei Shen, Jian He, Shumin Yang, Hongyan Si, Yi Wang, Zuhui Xu, Yunhong Tan, Tianzhu Chen, Weiguo Xu, Hong Peng, Zhijian Wang, Tao Zhu, Xinchun Chen, Yanlin Zhao*, Shiming Cheng*, Qi Jin*, for the LATENTTB-NSTM study team. Latent tuberculosis infection in rural China: baseline resultsof a population-based, multicentre, prospective cohortstudy. Lancet Infect Dis. 2015, 15(3):310-319. (IF=21.372, C100)

7. Feng Jiang, Nicholas R. Waterfield, Jian Yang, Guowei Yang*, Qi Jin*. A single Pseudomonas aeruginosa type VI secretion phospholipase D effector targets both prokaryotic and eukaryotic cells. Cell Host & Microbe, 2014,15(5):600-610. (IF=12.328, C100)

8. Haiying Chen#, Hui Yuan#, Rongbao Gao#, Jinxiang Zhang#, Dayan Wang#, Ying Xiong#, Guoyin Fan#, Fan Yang#, Xiaodan Li, Jiangfang Zhou, Shumei Zou, Lei Yang, Tao Chen, Libo Dong, Hong Bo, Xiang Zhao, Ye Zhang, Yu Lan, Tian Bai, Jie Dong, Qun Li, Shiwen Wang, Yanping Zhang, Hui Li, Tian Gong, Yong Shi, Xiansheng Ni, Jianxiong Li, Jun Zhou, Jiyi Fan, Jingwen Wu, Xianfeng Zhou, Maohong Hu, Jianguo Wan, Weizhong Yang, Dexin Li, Guizhen Wu, Zijian Feng, George F Gao, Yu Wang, Qi Jin*, Mingbin Liu*, Yuelong Shu*. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. Lancet, 2014,383: 714-721. (IF=45.217, C100)

9. Lihong Chen#, Jian Yang#, Jun Yu, Zhijian Yao, Lilian Sun, Yan Shen, Qi Jin*. VFDB: a reference database for bacterial virulence factors. Nucleic Acids Res. 2005, 33(suppl_1):D325-328. (IF=7.552, C100)

10.Qi Jin*, Zhenghong Yuan, Jianguo Xu, Yu Wang, Yan Shen, Weichuan Lu, Jinhua Wang, Hong Liu, Jian Yang, Fan Yang, Xiaobing Zhang, Jiyu Zhang, Guowei Yang, Hongtao Wu, Di Qu, Jie Dong, Lilian Sun, Ying Xue, Ailan Zhao, Yishan Gao, Junping Zhu, Biao Kan, Keyue Ding, Shuxia Chen, Hongsong Cheng, Zhijian Yao, Bingkun He, Runsheng Chen, Dalong Ma, Boqin Qiang, Yumei Wen, Yunde Hou, Jun Yu. Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genome of Escherichia coli K12 and O157.  Nucleic Acids Res. 2002, 30 (20):4432-4441. (IF=7.051, C100)