李卓荣，1962年生，籍贯河南省，药物化学家，医药生物技术研究所研究员，博士生导师。1983年获北京医学院药物化学专业学士学位。1985-1988年在中国协和医科大学微生物药学专业攻读硕士学位，从事抗感染药物研究。1992-1994年进入日本北里大学研修，主要研究抗生素的结构修饰；1997-1999年进入美国Oklahoma大学访问学者，主要研究激酶抑制剂抗肿瘤药物。 2000年起为研究员。

药物分子设计合成、活性筛选与构效关系研究及新药研发。主要研究方向：抗感染药物、神经系统药物和抗肿瘤药物设计与发现研究与品种研发。

皇冠足球90比分

1. Li Zeng#, Hailun Jiang#, Ghulam Md Ashraf, Jianghong Liu, Linlin Wang, Kaiyue Zhao, Mimin Liu, Zhuorong Li*, Rui Liu*. Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease. Mol Ther-Nucl Acids. 2022; 27:256–275. (IF=10.183)

2. Ting Sun#, Kaiyue Zhao#, Mimin Liu, Zhongdi Cai, Li Zeng, Junxia Zhang, Zhuorong Li*, Rui Liu*. miR-30a-5p induces Aβ production via inhibiting the nonamyloidogenic pathway in Alzheimer's disease. Pharmacol Res. 2022;178:106153. (IF=10.334)

3. Hailun Jiang#, Jianghong Liu#, Shuilong Guo#, Li Zeng, Zhongdi Cai, Junxia Zhang, Linlin Wang, Zhuorong Li*, Rui Liu*. miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways. Mol Ther-Nucl Acids. 2022;28:539–557. (IF=10.183)

4. Li Zeng#, Hai-Lun Jiang#, Ghulam Md Ashraf, Zhuo-Rong Li*, Rui Liu*. MicroRNA and messenger RNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing. Neural Regen Res. 2021;16 (10):2099–2108. (IF=6.058)

5. Si-tu Xuel#, Ke Li1, Yang Gao, Lu-yao Zhao, Yan Gao, Hong Yi, Jian-dong Jiang*, and Zhuo-rong Li*. The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target. Autophagy, 2020, 16:10, 1823-1837. (IF=10.643)

6. Xinbei Jiang#, Jiali Tan, YixuanWang, Jinhua Chen, Jianrui Li, Zhi Jiang, Yanni Quan, Jie Jin, Yuhuan Li, ShanCen, Yanping Li*, Zonggen Peng*, ZhuorongLi*. 2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as OrallyAvailable Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action. Journal of Medicinal Chemistry. 2020; 63(11):5972-5989. (IF =6.171)

7. A-Long Cui#, Xin-Xin Hu#, Yan Gao, Jie Jin, Hong Yi, Xiu-Kun Wang, Tong-Ying Nie, Yang Chen, Qi-Yang He, Hui-Fang Guo, Jian-Dong Jiang, Xue-Fu You*, Zhuo-Rong Li*. The Synthesis and Bioactivity Investigation of the Individual Components of Cyclic Lipopeptide Antibiotics. Journal of Medicinal Chemistry, 2018, 61, 1845-1857. (IF=6.034)

8. Xing-Yue Ji#, Jin-Hua Chen#, Guang-Hui Zheng, Meng-Hao Huang, Lei Zhang, Hong Yi, Jie Jin, Jian-Dong Jiang, Zong-Gen Peng*, Zhuo-Rong Li*. Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. J Med Chem. 2016 Nov 23;59(22):10268-10284. (IF=5.505)

9. Zong-Gen Peng#, Zhi-Yun Zhao#, Yan-Ping Li#, Yu-Ping Wang, Lan-Hu Hao, Bo Fan, Yu-Huan Li, Yue-Ming Wang, Yong-Qiang Shan, Yan-Xing Han, Yan-Ping Zhu, Jian-Rui Li, Xue-Fu You, Zhuo-Rong Li*, and Jian-Dong Jiang*. Host apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G is an innate defensive factor and drug target against hepatitis C virus. Hepatology. 2011 Apr; 53(4):1080-9. (IF=11.027)

10. Hui-fang Guo#, Hua-yi Shao#, Zhao-yong Yang#, Si-tu Xue, Xue Li, Zong-ying Liu, Xiao-bo He, Jian-dong Jiang, Yue-qin Zhang, Shu-yi Si*, and Zhuo-rong Li*. Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized rats. J Med Chem. 2010 Feb 25; 53(4):1819-29. (IF=4.865)