戴均贵，1969年生，籍贯湖北浠水，药物研究所研究员，博士生导师，研究方向为天然药物合成生物学。1987年考入华中师范大学生物学专业，1991年获学士学位；1993年在华中师范大学植物学专业攻读硕士学位；1996年在中国协和医科大学生药学专业攻读博士学位，从事天然药物生物合成研究。1999、2001年分别进入北京大学药学院、日本新泻大学化学系（JSPS）进行博士后研究工作，主要从事天然药物生物合成与生物催化研究。2004年为副研究员，2007年晋升为研究员。

针对天然药物面临的资源匮乏、成药性不足等关键科学问题，开展重要珍稀药用天然产物的生物合成与分子创新研究，揭示天然药物生物合成规律并重构生物合成途径，并实现可设计性、高效分子创新。

皇冠足球90比分

1. Yangyang Duan#, Wenyu Du#, Zhijun Song, Ridao Chen, Kebo Xie, Jimei Liu, Dawei Chen*, Jungui Dai*. Functional characterization of a cycloartenol synthase and four glycosyltransferases in the biosynthesis of cycloastragenol-type astragalosides from Astragalus membranaceus. Acta Pharmaceutica Sinica B, https://doi.org/10.1016/j.apsb.2022.05.015. (IF=14.903)

2. Lei Gao#, Cong Su#, Xiaoxia Du#, Ruishan Wang#, Shuming Chen, Yu Zhou, Chengwei Liu, Xiaojing Liu, Runze Tian, Liyun Zhang, Kebo Xie, She Chen, Qianqian Guo, Lanping Guo, Yoshio Hano, Manabu Shimazaki, Atsushi Minami, Hideaki Oikawa, Niu Huang, K. N. Houk, Luqi Huang*, Jungui Dai*, Xiaoguang Lei*. FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature Chemistry, 2020, 12 (7): 620–628. (IF=24.427, F1000)

3. Kebo Xie#*, Xiaolin Zhang#, Songyang Sui, Fei Ye*, and Jungui Dai*. Exploring and applying the substrate promiscuity of a C-glycosyltransferase in the chemo-enzymatic synthesis of bioactive C-glycosides. Nature Communications, 2020, 11 (1), 5162. (IF=14.919)

4. Dawei Chen, Shuai Fan, Ridao Chen, Kebo Xie, Sen Yin, Lili Sun, Jimei Liu, Lin Yang, Jianqiang Kong, Zhaoyong Yang, and Jungui Dai*. Probing and engineering key residues for bis-C-glycosylation and promiscuity of a C-glycosyltransferase. ACS Catalysis, 2018, 8 (6), 4917-4927. (IF=12.221)

5. Dawei Chen, Ridao Chen, Kebo Xie, Tian Yue, Xiaolin Zhang, Fei Ye, and Jungui Dai*. Biocatalytic C-glucosylation of coumarins using an engineered C-glycosyltransferase. Organic Letters, 2018, 20 (6), 1634-1637. (IF=6.555)

6. Ridao Chen#, Bingquan Gao#, Xiao Liu#, Feiying Ruan, Yong Zhang, Jizhong Lou, Keping Feng, Carsten Wunsch, Shu-Ming Li, Jungui Dai*, Fei Sun*. Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase. Nature Chemical Biology, 2017, 13 (2), 226-234. (IF=13.843, F1000)

7. Kebo Xie, Ridao Chen, Dawei Chen, Jianhua Li, Ruishan Wang, Lin Yang and Jungui Dai*. Enzymatic N-glycosylation of diverse arylamine aglycons by a promiscuous glycosyltransferase from Carthamus tinctorius. Advanced Synthesis & Catalysis, 2017, 359 (4), 603-608. (IF=5.123)

8. Dawei Chen, Ridao Chen, Ruishan Wang, Jianhua Li, Kebo Xie, Chuancai Bian, Lili Sun, Xiaolin Zhang, Jimei Liu, Lin Yang, Fei Ye, Xiaoming Yu, and Jungui Dai*. Probing the catalytic promiscuity of a regio- and stereo-specific C-glycosyltransferase from Mangifera indica. Angewandte Chemie International Edition, 2015, 54 (43), 12678-12682. (IF=11.709)

9. Dewu Zhang, Xiaoyu Tao, Ridao Chen, Jimei Liu, Li Li, Xiaomei Fang, Liyan Yu, and Jungui Dai*. Pericoannosin A, a polyketide synthase–nonribosomal peptide synthetase hybrid metabolite with new carbon skeleton from the endophytic fungus Periconia sp. Organic Letters, 2015, 17 (17), 4304-4307. (IF=6.732)

10. Ridao Chen, Xiao Liu, Jianhua Zou, Yunze Yin, Bin Ou, Jianhua Li, Ruishan Wang, Dan Xie, Peicheng Zhang, Jungui Dai*. Regio- and stereospecific prenylation of flavonoids by Sophora flavescens prenyltransferase. Advanced Synthesis & Catalysis, 2013, 355 (9), 1817–1828. (IF=5.542)